Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions
Yudong Gao, Matthew Trn, Daichi Shonai, Jieqing Zhao, Erik J. Soderblom, S. Alexandra Garcia-Moreno, Charles A. Gersbach, William C. Wetsel, Géraldine Dawson, Dmitry Velmeshev, Yong‐hui Jiang, Laura Gail Sloofman, Joseph D. Buxbaum, Scott H. Soderling
The paper develops a proximity proteomics method in mice to identify protein interactions relevant to autism, revealing new genetic risk factors and functional interactions.
bioRxiv · Oct 6, 2022 · PreprintNeuroscience