Author

S. Alexandra Garcia-Moreno

Duke Medical CenterORCID 0000-0003-2137-6114Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Blanche CapeliD· 2 shared A. Marc· 1 shared Alicia HurtadoiD· 1 shared Capel Blanche Acemel· 1 shared Charles A. GersbachiD· 1 shared Christopher R. FuttneriD· 1 shared D. De Rafael· 1 shared D. Rafael Real· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Blanche CapelORCID

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3 papers

Recent·Most cited

Developmental BiologyNature Structural & Molecular BiologyPeer-reviewedFeb 24, 2026

Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis

Irene Mota-Gómez, Juan Antonio Rodríguez, Shannon M. Dupont…·Darío G. Lupiáñez

The paper identifies 3D regulatory hubs involved in sex determination using spatial auto-correlation analysis in mouse embryos.

2 citationstop 4%

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 6, 2022

Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions

Yudong Gao, Matthew Trn, Daichi Shonai…·Scott H. Soderling

The paper develops a proximity proteomics method in mice to identify protein interactions relevant to autism, revealing new genetic risk factors and functional interactions.

2 citations

mouseproteomics

𝕏 PostBluesky

Developmental BiologyPLoS GeneticsPeer-reviewedMay 22, 2019

CBX2 is required during male sex determination to repress female fate at bivalent loci

S. Alexandra Garcia-Moreno, Yi-Tzu Lin, Christopher R. Futtner…·Blanche Capel

This study shows that CBX2 represses female fate by maintaining bivalent female-determining genes in male gonads, enabling Sry expression and testis development.

79 citationstop 3%

𝕏 PostBluesky