Yudong Gao

This study identifies Paralemmin 2 as a lipid raft-associated protein that regulates axon initial segments and paranodal junctions through cell type-specific splicing.

The paper uses in vivo proteomics and CRISPR screening to identify STXBP1 as a protective factor against α-synuclein toxicity in dopamine neurons in Parkinson's disease models.

The paper identifies new ciliary signaling pathways in the mouse brain using iBioID and links them to neurological disorders.

The paper develops a proximity proteomics method in mice to identify protein interactions relevant to autism, revealing new genetic risk factors and functional interactions.

This study identifies Rac1 and Arp2/3 as key regulators of presynaptic plasticity through proteomic analysis and shows their coupling to action potentials via calcium influx.