Inhibitors of HIV-1 maturation modulate conformational dynamics and heterogeneity of the immature Gag lattice
Tathagata Nandi, Matthew Wong, Abdul A. Waheed, Eric O. Freed, Celia A. Schiffer, James B. Munro
This study uses single-molecule imaging to show that maturation inhibitors alter Gag conformational dynamics and spatial heterogeneity in immature HIV-1 virions.
bioRxiv · Sep 12, 2026 · PreprintBiophysics