TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
Chenhao Tong, Tao Lin, Han Wang, C de la Torre, Hui Liu, Chen Shao, Seddik Hammad, Roman Liebe, Matthias P Ebert, Huiguo Ding, Steven Dooley, Honglei Weng
This study identifies TGF-β as a key regulator of liver progenitor cell quiescence and activation, showing its dual role in inhibiting proliferation while being counteracted by HGF and EGF signals.
Zeitschrift für Gastroenterologie · Sep 1, 2025Peer-reviewedCell Biology