Abhilesh S Dhawanjewar

The paper shows that tissue-wide metabolic buffering allows neural stem cells to maintain proliferation despite mitochondrial dysfunction, highlighting the role of tissue heterogeneity in resilience.

This study develops mRNA-LNP therapy for MNGIE, restoring nucleoside balance and TP expression in mice through subcutaneous delivery.

The paper uses single-molecule FISH to study mtDNA heteroplasmy dynamics in Drosophila and human cells, revealing developmental bottlenecks and selection effects on mutation load.

This paper introduces PIZSA, a scoring function to assess protein-protein interaction stability, which outperforms existing methods in distinguishing native from non-native conformations.