Sialidases derived from Gardnerella vaginalis and Prevotella Timonensis remodel the sperm glycocalyx and impair sperm function
Sarah Dohadwala, Purna Shah, Maura K Farrell, Joseph A. Politch, Jai G. Marathe, Catherine E. Costello, Deborah Jean Anderson
This study shows that sialidases from BV-associated bacteria damage the sperm glycocalyx, increasing susceptibility to agglutination and impairing cervical mucus transit.
Glycobiology · Oct 30, 2025Peer-reviewedImmunology