Author

Sarah Dohadwala

Boston UniversityORCID 0000-0002-7003-0796Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Catherine E. CostelloiD· 2 shared Deborah Jean AndersoniD· 2 shared Joseph A. PolitchiD· 2 shared Purna Shah· 2 shared Alexi G. ChoueiriiD· 1 shared Camille Marie MitchelliD· 1 shared Chaoshuang XiaiD· 1 shared Chi ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Catherine E. CostelloORCID

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3 papers

Recent·Most cited

The Human Contraceptive Antibody Targets A Semenogelin Galectin-3 N-Linked Glycan Complex on the Sperm Surface

Sarah Dohadwala, Chaoshuang Xia, Shane Finn, Purna Shah, Shang‐Chuen Wu, Hau Ming Jan, Joseph A. Politch, Kevin J. Whaley, Sean R. Stowell, Stacy Alyse Malaker, Catherine E. Costello, Deborah Jean Anderson

This paper identifies the HCA antibody's target as a semenogelin-galectin-3 complex on the sperm surface, rather than CD52, through affinity purification and glycan analysis.

bioRxiv · Oct 14, 2026 · PreprintImmunology

Principles of in situ protein sequencing: expansion microscopy-adapted Edman degradation and amino acid recognition

Camille Marie Mitchell, Sara Z. Tavana, Joanne Peng, Hao Wang, Jiuhan Shi, Chi Zhang, Lilia Evgeniou, Masy Domecillo, Shiwei Wang, Daniel Estandian, Alexi G. Choueiri, E. Wong, Sarah Dohadwala, Isken Kenzhebaev, Tay Won Shin, , Edward S. Boyden

This study adapts Edman degradation and amino acid recognition to expansion microscopy gels to demonstrate in situ protein sequencing principles using synthetic constructs.

bioRxiv · Jul 21, 2026 · PreprintBiochemistry

Sialidases derived from Gardnerella vaginalis and Prevotella Timonensis remodel the sperm glycocalyx and impair sperm function

Sarah Dohadwala, Purna Shah, Maura K Farrell, Joseph A. Politch, Jai G. Marathe, Catherine E. Costello, Deborah Jean Anderson

This study shows that sialidases from BV-associated bacteria damage the sperm glycocalyx, increasing susceptibility to agglutination and impairing cervical mucus transit.

Glycobiology · Oct 30, 2025Peer-reviewedImmunology