Author

Maureen Legendre

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

David M. MarkovitziD· 2 shared Alnawaz RehemtullaiD· 1 shared Ang Lin· 1 shared Anna Smed‐SörenseniD· 1 shared Anupama PaliD· 1 shared Dafydd G. ThomasiD· 1 shared Ebba SohlbergiD· 1 shared Evelyn M. Covés-DatsoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

David M. MarkovitzORCID

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2 papers

Recent·Most cited

A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion

Meng Yu, Ang Lin, Faezzah Baharom, Shuijie Li, Maureen Legendre, Evelyn M. Covés-Datson, Ebba Sohlberg, Susanne Schlisio, Karin Loré, David M. Markovitz, Anna Smed‐Sörensen

This study evaluates the antiviral and immunomodulatory effects of H84T BanLec on human immune cells and IAV-specific CD8 T cell responses.

PLoS Pathogens · May 7, 2025Peer-reviewedImmunology

A molecularly engineered lectin destroys EGFR and inhibits the growth of non-small cell lung cancer

Susana M. Chan, Zoe Raglow, Anupama Pal, Scott D. Gitlin, Maureen Legendre, Dafydd G. Thomas, Ranjit Kumar Mehta, Mingjia Tan, Mukesh Kumar Nyati, Alnawaz Rehemtulla, David M. Markovitz

This paper demonstrates that the engineered lectin H84T binds to and inhibits NSCLC cell growth by lysosomal degradation of EGFR, independent of EGFR mutation status.

bioRxiv · Mar 18, 2024 · PreprintCancer Biology