Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription
G Fernandes, Huy Tran, Maxime Andrieu, Youssoupha Diaw, Carmina Angelica Perez-Romero, Cécile Fradin, Mathieu Coppey, Aleksandra M. Walczak, Nathalie Dostatni
The paper shows that the Bicoid-hunchback system's transcription dynamics can be explained by an equilibrium model with Bicoid as the sole positional information source, with Zelda and Hunchback modulating the process.
eLife · Mar 11, 2022Peer-reviewedDevelopmental Biology