Mathieu Coppey

The paper quantifies information transduced through the ERK pathway in single cells and populations, showing single cells can resolve graded stimuli with over 2 bits of information.

The paper uses magnetic micromanipulation to show Rab25 vesicles directly drive F-actin protrusions, enhancing cancer cell invasive migration.

The paper shows that the Bicoid-hunchback system's transcription dynamics can be explained by an equilibrium model with Bicoid as the sole positional information source, with Zelda and Hunchback modulating the process.

The paper measures Bicoid morphogen concentration dynamics in fruit fly embryos using a modified MS2-MCP reporter and shows that a 750 bp promoter region can recapitulate endogenous expression with high precision within 3 minutes.

The paper studies transcription dynamics of the hunchback gene in Drosophila embryos using imaging data and identifies bursty transcription initiation and low expression precision.