Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury
Julius Clemens Fischer, Sascha Göttert, Maximilian Giller, Paul Heinrich, Kaiji Fan, Omer Khalid, Caroline N. Walther, Maria Drießlein, Sophie M. Nefzger, Gabriel Eisenkolb, Vincent R. Timnik, Sebastian Jarosch, Lena Klostermeier, Thomas Engleitner, Nicholas Strieder, , Hendrik Poeck
The paper shows that Treg cells use IFNγ and IL-10 to promote intestinal stem cell growth and repair after injury.
Signal Transduction and Targeted Therapy · Nov 25, 2025Peer-reviewedImmunology