Author

Thomas Engleitner

Technical University of MunichORCID 0000-0002-7989-681XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Assay:proteomics· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Roland RadiD· 3 shared Albrecht StenzingeriD· 1 shared Alexander KlegeriD· 1 shared Alexey StukaloviD· 1 shared Alica K. Beutel· 1 shared Alireza AbaeiiD· 1 shared Andreas PichlmairiD· 1 shared Anna HärleiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Roland RadORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury

Julius Clemens Fischer, Sascha Göttert, Maximilian Giller, Paul Heinrich, Kaiji Fan, Omer Khalid, Caroline N. Walther, Maria Drießlein, Sophie M. Nefzger, Gabriel Eisenkolb, Vincent R. Timnik, Sebastian Jarosch, Lena Klostermeier, Thomas Engleitner, Nicholas Strieder, , Hendrik Poeck

The paper shows that Treg cells use IFNγ and IL-10 to promote intestinal stem cell growth and repair after injury.

Signal Transduction and Targeted Therapy · Nov 25, 2025Peer-reviewedImmunology

Exploiting TGF-β-mediated Stromal Programming in Homologous Recombination-Deficient Pancreatic Cancer

Élodie Roger, Hannah M Mummey, Eleni Zimmer, Dharini Srinivasan, Anna Härle, Loïc Moubri, Alica K. Beutel, Rima Singh, Menar Ekizce, Michael Karl Melzer, Yun Jung Lee, Austin Silva, Luisa Härle, Thomas Engleitner, Frank Arnold, , Alexander Kleger

This study shows that ATM-deficient pancreatic cancers reprogram the tumor microenvironment via TGF-β-driven myCAF enrichment, and targeting this stromal axis with chemotherapy improves therapeutic efficacy.

bioRxiv · Sep 16, 2025 · PreprintCancer Biology

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

Alexey Stukalov, Virginie Girault, Vincent Grass, Özge Karayel, Valter Bergant, Christian Urban, Darya A. Haas, Yiqi Huang, Lila Oubraham, Anqi Wang, M. Sabri Hamad, Antonio Piras, Fynn M. Hansen, Maria C. Tanzer, Igor Paron, , Andreas Pichlmair

Concurrent multi-omics of SARS-CoV-2 and SARS-CoV in A549 cells, integrated by network diffusion, maps shared and virus-specific host perturbations and nominates antiviral drug hotspots.

Nature · Apr 12, 2021Peer-reviewedSystems Biology✦ In-depth digest