Computational design of structurally diverse antibody repertoires with drug-like properties
Ariel Tennenhouse, Rebecca E Wilen, Sveta Gaiduk, Roman Kamyshinsky, Sarah Borni, Mazal Faraj, Eliane Hadas Yardeni, Moshe Goldsmith, Inbar Cahana, Shira Albeck, Tamar Unger, Rony Dahan, Ron Diskin, Sarel Jacob Fleishman
The paper designs structurally diverse antibody repertoires with drug-like properties using a computational method called CADAbRe, demonstrating their utility in binding to challenging targets.
bioRxiv · Jul 13, 2026 · PreprintSynthetic Biology