Moshe Goldsmith

The paper shows DNA-bound Egr-1 delays RNA polymerase elongation through kinetic destabilization, with CpG methylation reducing this delay.

The paper designs structurally diverse antibody repertoires with drug-like properties using a computational method called CADAbRe, demonstrating their utility in binding to challenging targets.

The paper compares three data analysis methods for MERS-CoV MPro inhibitors, finding that modeling the complete concentration-response curve best predicts cellular efficacy.

The paper identifies viral proteins that manipulate bacterial immune signaling by analyzing structural and biophysical traits, and develops a computational pipeline to predict such proteins in phage genomes.

This study shows that intrinsically disordered regions in Msn2 enhance DNA binding and promoter selectivity through non-specific association and one-dimensional diffusion.