NeurosciencebioRxivPreprint
INSULIN-LIKE GROWTH FACTOR I MODULATES VULNERABILITY TO STRESS THROUGH OREXIN NEURONS
ME Fernandez de Sevilla, Jaime Pignatelli, Pablo Méndez…·I Torres Alemán
This study shows that IGF-I modulates stress vulnerability via orexin neurons, with Firoc mice lacking IGF-I receptors in these neurons showing heightened fear responses and PTSD-like behaviors.
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