origamiFISH allows universal, label-free, single molecule visualization of DNA origami nanodevices across biological samples
Wendy Xueyi Wang, Travis R. Douglas, Haiwang Zhang, Afrin Bhattacharya, Meghan Rothenbroker, Wentian Tang, Yu Sun, Zhengping Jia, Julien Muffat, Yun Li, Leo Y. T. Chou
origamiFISH enables label-free, single-molecule detection of DNA origami nanostructures in cells and tissues, revealing cell-type and shape-specific uptake patterns at low concentrations.
Nature Nanotechnology · Jul 27, 2023Peer-reviewedSynthetic Biology