Wendy Xueyi Wang

The paper uses spatial omics to analyze translational dysregulation in Grin2a+/- mice, finding gene-specific translation reductions in neurons and non-neuronal cells linked to schizophrenia pathophysiology.

This paper develops Deep-STARmap and Deep-RIBOmap for 3D spatial transcriptomics and translatomics in thick tissue blocks, enabling analysis of gene expression and immune interactions in human skin cancer.

The paper introduces FuseMap, a deep-learning framework for spatial transcriptomics that creates a comprehensive molecular spatial reference atlas of the mouse brain.

origamiFISH enables label-free, single-molecule detection of DNA origami nanostructures in cells and tissues, revealing cell-type and shape-specific uptake patterns at low concentrations.

The paper uses morphology-based pseudotime and fate mapping to show cerebellar inhibitory interneurons diversify into two classes with within-class heterogeneity.

This study shows that gamma-Protocadherins are essential for the survival of GABAergic interneurons during development, preventing excessive apoptosis and ensuring proper inhibitory network formation.