Author

Afrin Bhattacharya

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Julien MuffatiD· 2 shared Yun LiiD· 2 shared Aditi Aggarwal· 1 shared Ai TianiD· 1 shared Guoria Sun· 1 shared Haiwang ZhangiD· 1 shared Haruka NishimuraiD· 1 shared Leo Y. T. ChouiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Julien MuffatORCID

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2 papers

Recent·Most cited

ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation

Navroop K. Dhaliwal, Octavia Yifang Weng, Ai Tian, Aditi Aggarwal, Mai Essam Ahmed, Guoria Sun, Afrin Bhattacharya, Wendy W. Y. Choi, Haruka Nishimura, Pragnya Chakraborty, Xiaoxue Dong, Yuncheng Wu, Michael D. Wilson, Lu‐Yang Wang, Luis F. Parada, , Yun Li

This study identifies the ARP2/3 complex as a downstream effector of mTORC1 and mTORC2 hyperactivation in PTEN-deficient neural cells, showing its inhibition can rescue disease phenotypes.

Proceedings of the National Academy of Sciences · Feb 12, 2026Peer-reviewedNeuroscience

origamiFISH allows universal, label-free, single molecule visualization of DNA origami nanodevices across biological samples

Wendy Xueyi Wang, Travis R. Douglas, Haiwang Zhang, Afrin Bhattacharya, Meghan Rothenbroker, Wentian Tang, Yu Sun, Zhengping Jia, Julien Muffat, Yun Li, Leo Y. T. Chou

origamiFISH enables label-free, single-molecule detection of DNA origami nanostructures in cells and tissues, revealing cell-type and shape-specific uptake patterns at low concentrations.

Nature Nanotechnology · Jul 27, 2023Peer-reviewedSynthetic Biology