Vascular Injury Changes Topology of Vessel Network to Adapt to Partition of Blood Flow for New Arteriovenous Specification
Kyung In Baek, Shyr-Shea Chang, Chih‐Chiang Chang, Mehrdad Roustei, Yichen Ding, Yixuan Wang, Justin Chen, Ryan O’donnelle, Hong Chen, Julianne W. Ashby, Julia J. Mack, Xiaolei Xu, Susana Cavallero, Marcus L. Roper, Tzung K. Hsiai
The paper shows that vascular injury leads to changes in vessel network topology to increase blood flow and activate Notch-ephrinb2 signaling for microcirculation restoration.
bioRxiv · Jun 9, 2020 · PreprintMolecular Biology