Author

Shyr-Shea Chang

Rockefeller UniversityORCID 0000-0002-7123-4264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:CUT&Tag· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Chih‐Chiang Chang· 1 shared Eric D. SiggiaiD· 1 shared Hong CheniD· 1 shared Julia J. MackiD· 1 shared Julianne W. AshbyiD· 1 shared Justin CheniD· 1 shared Kyung In BaekiD· 1 shared Marcus L. RoperiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Chih‐Chiang Chang

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2 papers

Recent·Most cited

A landscape model for cell fate decisions during mesoendoderm differentiation in C. elegans based on Wnt dynamics

Shyr-Shea Chang, Zhirong Bao, Eric D. Siggia

The paper constructs a Waddington landscape model to predict cell fate decisions during C. elegans mesoendoderm differentiation based on Wnt dynamics and mutant penetrance data.

bioRxiv · Jun 9, 2021 · PreprintDevelopmental Biology

Vascular Injury Changes Topology of Vessel Network to Adapt to Partition of Blood Flow for New Arteriovenous Specification

Kyung In Baek, Shyr-Shea Chang, Chih‐Chiang Chang, Mehrdad Roustei, Yichen Ding, Yixuan Wang, Justin Chen, Ryan O’donnelle, Hong Chen, Julianne W. Ashby, Julia J. Mack, Xiaolei Xu, Susana Cavallero, Marcus L. Roper, Tzung K. Hsiai

The paper shows that vascular injury leads to changes in vessel network topology to increase blood flow and activate Notch-ephrinb2 signaling for microcirculation restoration.

bioRxiv · Jun 9, 2020 · PreprintMolecular Biology