Sonja Blasche

This study shows that the antidepressant duloxetine disrupts RNA-protein interactions in both human and bacterial cells, revealing a new mechanism of drug action.

This study investigates interactions between low-calorie sweeteners and xenobiotics on gut bacteria, finding synergistic effects that alter bacterial growth and host cell responses.

The paper shows how oxygen gradients in the gut reshape cross-feeding between Bacteroides thetaiotaomicron and Escherichia coli through spatial organization and metabolic feedback.

This study investigates the off-target antibacterial effects of 1076 industrial and agricultural chemicals on 22 human gut bacteria, revealing 588 previously unreported interactions.

This paper combines cryo-EM and FIB-SIMS to map sub-cellular chemical distributions in bacteria, revealing pollutant storage in phase-separated aggregates.

This study shows human gut bacteria can accumulate PFAS, with some species like Bacteroides uniformis accumulating them to high concentrations, and identifies mechanisms involving transmembrane transport and efflux pumps.

This study examines how bacterial proteomes and metabolomes change in response to interspecies interactions in gut microbiota co-cultures, revealing extensive molecular reorganization and emergent metabolic pathways.

The paper shows how species in gut bacterial communities can survive or go extinct based on resource availability and metabolic interactions, identifying emergent survival and community-driven extinctions.