Author

Meirav Avital‐Shacham

University of Haifa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Mickey KosloffiD· 2 shared Andreea NissenkorniD· 1 shared Christian Le GouilliD· 1 shared Dina Schneidman‐DuhovnyiD· 1 shared Ehud BanneiD· 1 shared Irina NekrasovaiD· 1 shared Isra SadiyaiD· 1 shared Keren ZohariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Mickey KosloffORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 3, 2025

Deciphering the mechanistic basis for the pathological effect of the Gαo E246K mutation in neurodevelopmental disorder

Isra Sadiya, Irina Nekrasova, Meirav Avital‐Shacham…·Mickey Kosloff

The paper investigates the molecular mechanism of the Gαo E246K mutation in neurodevelopmental disorders, showing it disrupts the GTPase cycle by impairing Gβγ dissociation, leading to dominant-negative effects.

DOI 10.1101/2025.09.03.673757

humanproteomics

𝕏 PostBluesky

BiochemistryFEBS JournalPeer-reviewedMay 28, 2025

Gαs-specific structural elements attenuate interactions with RGS proteins

Sabreen Higazy‐Mreih, Meirav Avital‐Shacham, Christian Le Gouill…·Mickey Kosloff

The paper identifies structural elements in Gαs that prevent interactions with RGS proteins, showing three residues in the GTPase domain are necessary and sufficient for this resistance.

1 citation

proteomicsexperimental assay

𝕏 PostBluesky