Author

Melani D. Peralta

Instituto de Biología Molecular y Celular de Rosario

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

David SychanthaiD· 1 shared Gerard D. WrightiD· 1 shared Irina P. SuáreziD· 1 shared Kalinka K. KotevaiD· 1 shared Leticia Irene LlarrulliD· 1 shared Melisa B. Antinori· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

David SychanthaORCID

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1 paper

Recent·Most cited

The histidine kinase VraS orchestrates the cell-wall stress response in Staphylococcus aureus via its direct interaction with glycopeptides and β-lactams

Melisa B. Antinori, David Sychantha, Kalinka K. Koteva, Irina P. Suárez, Melani D. Peralta, Gerard D. Wright, Leticia Irene Llarrull

This study identifies VraS as a direct receptor for vancomycin and ampicillin, revealing its role in activating the cell-wall stress response in Staphylococcus aureus and providing a target for combating antibiotic resistance.

bioRxiv · Jan 23, 2025 · PreprintBiochemistry