Leticia Irene Llarrull

This study reveals how β-lactam antibiotics interact with the histidine kinase VbrK through redox-dependent cysteine acylation, enabling bacterial resistance.

This study identifies VraS as a direct receptor for vancomycin and ampicillin, revealing its role in activating the cell-wall stress response in Staphylococcus aureus and providing a target for combating antibiotic resistance.