Author

Melanie A. Orlando

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

Benjamin J. OrlandoiD· 2 shared Matthew W. Faber· 1 shared Peixuan Yu· 1 shared Samik BoseiD· 1 shared Tejas V. ShahiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

Benjamin J. OrlandoORCID

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2 papers

Recent·Most cited

BiophysicsProtein SciencePeer-reviewedAug 19, 2026

Structure and conformational dynamics of the Pseudomonas CbrA transceptor

Melanie A. Orlando, Tejas V. Shah, Matthew W. Faber…·Benjamin J. Orlando

This paper determines the cryo-EM structure of CbrA, revealing its SLC5-STAC domains and how CbrX interacts with the transporter, providing insights into histidine transport and signaling mechanisms.

DOI 10.1002/pro.70775

bacteria (other)cryo-EM

𝕏 PostBluesky

BiochemistryCommunications BiologyPeer-reviewedJul 18, 2025

Structure and Post-Translational Modification of the Prostaglandin Transporter

Peixuan Yu, Melanie A. Orlando, Benjamin J. Orlando

This paper determines the cryo-EM structure of human PGT and identifies disulfide bonds critical for its function and post-translational modifications.

3 citations

humanstructural biology

𝕏 PostBluesky