Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
Suzuki Ken, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Nigel W. Rayner, Ozvan Bocher, S. V. Arruda Ana Luiza de, Kyuto Sonehara, Shinichi Namba, Simon S. K. Lee, Michael H. Preuss, , H. Janaka de Silva
This study identifies 1,289 genetic signals for type 2 diabetes in 2.5 million individuals, revealing distinct clusters linked to vascular complications and highlighting ancestry-specific genetic risk factors.
Yearbook of pediatric endocrinology · Sep 8, 2023Peer-reviewedGenetic & Genomic Medicine