Author

Weihua Zhang

Ealing Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:GWAS summary statistics· 3 Research Focus:fine-mapping· 2 Research Focus:GWAS / association mapping· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Jennifer A. BrodyiD· 4 shared Jie YaoiD· 4 shared Lawrence F. BielakiD· 4 shared Brian E. CadeiD· 3 shared Chien-Hsiun CheniD· 3 shared Ivan BrandslundiD· 3 shared Jirong LongiD· 3 shared Li-Ching ChangiD· 3 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Jennifer A. BrodyORCID

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Author profile →

4 papers

Recent·Most cited

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

Suzuki Ken, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Nigel W. Rayner, Ozvan Bocher, S. V. Arruda Ana Luiza de, Kyuto Sonehara, Shinichi Namba, Simon S. K. Lee, Michael H. Preuss, , H. Janaka de Silva

This study identifies 1,289 genetic signals for type 2 diabetes in 2.5 million individuals, revealing distinct clusters linked to vascular complications and highlighting ancestry-specific genetic risk factors.

Yearbook of pediatric endocrinology · Sep 8, 2023Peer-reviewedGenetic & Genomic Medicine

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Anubha Mahajan, Cassandra Nichole Spracklen, Weihua Zhang, Maggie C.Y. Ng, Lauren E. Petty, Hidetoshi Kitajima, Grace Z. Yu, Sina Rüeger, Leo Speidel, Young Jin Kim, Momoko Horikoshi, Josep Maria Mercader, Daniel Taliun, Sanghoon Moon, Soo‐Heon Kwak, , Mary Cushman

This study identifies 277 T2D loci using diverse populations and improves fine-mapping to assess causal genes and mechanisms, enhancing clinical translation.

Discovery Research Portal (University of Dundee) · Jan 1, 2022Peer-reviewedGenetic & Genomic Medicine

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

Ji Chen, Cassandra Nichole Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J. Corbin, Jian’an Luan, Sara M. Willems, Ying Wu, Xiaoshuai Zhang, Momoko Horikoshi, Thibaud Boutin, Reedik Mägi, Johannes Waage, Achilleas Pitsillides, Ruifang Li‐Gao, , Michael H Preuss

This study identifies 242 genetic loci for glycaemic traits using trans-ancestry meta-analysis, finding 99 novel loci and improved fine-mapping resolution compared to single-ancestry analyses.

bioRxiv · Jul 23, 2020 · PreprintGenetics

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

Natasha Hui Jin Ng, Sara M. Willems, Juan Fernandez, Rebecca S. Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaëlle Marenne, Jana K. Rundle, Xueling Sim, Hanieh Yeghootkar, Nicola L. Beer, Anne Raimondo, Andrei I. Tarasov, Soren K. Thomsen, , Abbas Dehghan

The paper identifies genetic variants and transcripts associated with glycemic traits by analyzing exome-array data from 144,600 individuals, highlighting tissue-specific roles in glucose regulation.

bioRxiv · Oct 3, 2019 · PreprintGenetics