Author

Mengzhen Li

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Adil MardinoğluiD· 1 shared Cheng JiniD· 1 shared Cheng ZhangiD· 1 shared Dingfeng Zou· 1 shared Han WangiD· 1 shared Hasan TürkeziD· 1 shared Hengxin Liu· 1 shared Jia YuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Adil MardinoğluORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systematic Analysis of Human Tissue- and Cell-Specific Metabolic Models Identifies High-Sugar, High Fat Diet Induced Liver Dysregulation

Mengzhen Li, Mengnan Shi, Cheng Zhang, Hasan Türkez, Mathias Uhlén, Adil Mardinoğlu

The paper constructs tissue- and cell-type-specific metabolic models to study the effects of a high-sugar, high-fat diet on liver metabolism, revealing metabolic reprogramming and dysfunction.

bioRxiv · Feb 19, 2026 · PreprintBioinformatics

Large-scale single-cell long-read genomics enables high-resolution microbiome profiling

Mengzhen Li, Shiyan Li, Hengxin Liu, Xuanpei Zhai, Jie Li, Yanan Du, Xiaolu Li, Jiawei Tong, Jian Zhang, Rong Zhang, Zhangyue Song, Quanjiang Ji, Yuan Luo, Ting Zhang, Wei Wu, Yifan Liu

The paper introduces CAP-seq, a single-cell genomics platform for microbiome analysis, demonstrating strain-level resolution and high genome recovery from microbial communities.

bioRxiv · Sep 10, 2024 · PreprintGenomics

Identification of quiescent FOXC2+ spermatogonial stem cells in adult mammals

Zhipeng Wang, Cheng Jin, Pengyu Li, Yiran Li, Jielin Tang, Zhixin Yu, Tao Jiao, Jinhuan Ou, Han Wang, Dingfeng Zou, Mengzhen Li, Xinyu Mang, Jun Liu, Yan Lü, Kai Li, , Wei Song

The paper identifies quiescent FOXC2+ spermatogonial stem cells in adult mammals and shows their critical role in maintaining spermatogenesis homeostasis and regeneration.

eLife · Aug 23, 2023Peer-reviewedDevelopmental Biology