Author

Xiaolu Li

Pacific Northwest National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Microbiology· 1 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Weijun QianiD· 3 shared Jordan C. RozumiD· 2 shared Pavlo BohutskyiiD· 2 shared Abdalla AhmediD· 1 shared Akshay BarejaiD· 1 shared Amity AnderseniD· 1 shared Andrea Lynn HeveneriD· 1 shared August GeorgeiD· 1 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Weijun QianORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell State Transitions Drive Transcriptome-Proteome Alignment in a Minimal Photoautotroph

Jordan C. Rozum, Xiaolu Li, Young‐Mo Kim, Zachary Johnson, William Sineath, Marci Garcia, Natalie Sadler, Pavlo Bohutskyi, Margaret Cheung, Wei-Jun Qian, Song Feng

The paper investigates how cell state transitions in Prochlorococcus marinus MED4 affect transcriptome-proteome alignment through regulatory mechanisms involving RpaB and HimA.

bioRxiv · Oct 21, 2026 · PreprintSystems Biology

Cyanophage CP12 Rewires Host Carbon Regulation through Interface Remodeling and Redox Buffering

Scott Widmann, Ruonan Wu, Malio Nelson, Daniel Mejı́a-Rodrı́guez, Suman Samantray, Reece Neff, Song Feng, Xiaolu Li, Jordan C. Rozum, August George, Paul Rigor, Pavlo Bohutskyi, Noelani R Boise, Ho Shin Kim, Lindsey N Anderson, , Margaret S. Cheung

This study investigates how cyanophage CP12 modulates host carbon regulation by remodeling interfaces and buffering redox changes during infection.

bioRxiv · Sep 11, 2026 · PreprintMicrobiology

Integrated Post-Translational Modification (PTM) Proteomics Reveals Early Redox and Mitochondrial Remodeling Following Ref-1 Inhibition in Pancreatic Cancer

Silpa Gampala, xiaolu Li, Jesse B. Trejo, Marina Gritsenko, Rosalie Chu, Weijun Qian, Elizabeth A. Sierra Potchanant, Melissa L. Fishel, Tong Zhang, Mark R. Kelley

This paper uses integrated PTM proteomics to show that Ref-1 inhibition rapidly remodels redox and mitochondrial signaling in pancreatic cancer cells.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

Temporal Multi-Omic Analysis Uncovers Sex-Biased Molecular Programs Underlying Skeletal Muscle Adaptation to Endurance Training

Gina M. Many, Christopher A. Jin, Nicholas J. Day, Gayatri R. Iyer, Gergory Smith, Kayleigh M. Voos, James A. Sanford, Akshay Bareja, David Jimenez‐Morales, Damon T. Leach, Tyler J. Sagendorf, Abdalla Ahmed, Xiaolu Li, Matthew J. Gaffrey, Isaac Kwame Attah, , Maléne E. Lindholm

This study identifies shared and sex-specific molecular responses to endurance training in skeletal muscle using multi-omics data from rats.

Cell Reports · Aug 1, 2026Peer-reviewedPhysiology

Large-scale single-cell long-read genomics enables high-resolution microbiome profiling

Mengzhen Li, Shiyan Li, Hengxin Liu, Xuanpei Zhai, Jie Li, Yanan Du, Xiaolu Li, Jiawei Tong, Jian Zhang, Rong Zhang, Zhangyue Song, Quanjiang Ji, Yuan Luo, Ting Zhang, Wei Wu, Yifan Liu

The paper introduces CAP-seq, a single-cell genomics platform for microbiome analysis, demonstrating strain-level resolution and high genome recovery from microbial communities.

bioRxiv · Sep 10, 2024 · PreprintGenomics