Hasan Türkez

The paper constructs tissue- and cell-type-specific metabolic models to study the effects of a high-sugar, high-fat diet on liver metabolism, revealing metabolic reprogramming and dysfunction.

This study investigates the effects of JNK inhibition on metabolic dysfunction caused by sucrose overconsumption in rats using multi-tissue network analysis.

This study identifies PKLR as a therapeutic target for NAFLD and validates two drug candidates through in vitro and in vivo experiments.

This study sequenced and analyzed 1000 SARS-CoV-2 genomes from Turkey to track mutations and lineage distribution across regions and time.

This study identifies dysregulated transcriptional regulators in NAFLD using network analysis and integrates transcriptomic data with metabolic models.

This study identifies retinoids and sex hormone dysregulation as ageing-related features in Alzheimer's and Parkinson's disease subclasses using transcriptomic and metabolic analyses.

The paper analyzes transcriptomic changes in heart and other metabolically active tissues after myocardial infarction in mice, identifying common and tissue-specific biological responses.

iNetModels 2.0 provides an interactive platform for visualizing and exploring multi-omics associations in human health and disease.

The paper investigates the prognostic significance of PKM transcripts in 25 cancers and identifies a prognostic signature in KIRC, revealing functional roles of alternatively spliced PKM transcripts.

The paper identifies two ccRCC subtypes based on PKM alternative splicing and proposes drug repurposing for each subtype.