Rong Zhang

The paper develops ConMeter, a metabolite prediction model, and uses it to design an orally bioavailable RSK4 inhibitor with improved bioavailability and anti-tumor efficacy against esophageal cancer.

This study identifies miR-145-5p as a mediator of renal tubule epithelial cell apoptosis in ARDS via the JNK pathway.

The paper introduces CAP-seq, a single-cell genomics platform for microbiome analysis, demonstrating strain-level resolution and high genome recovery from microbial communities.

The paper reports oscillatory behavior in a self-activation gene circuit induced by nutrient-modulating growth feedback and validates it with a mathematical model.

This study identifies ROCK1-regulated mitochondrial fission as a key mechanism in dopaminergic nerve cell apoptosis in Parkinson's disease.