PD-1 endocytosis unleashes the cytolytic potential of check-point blockade in tumor immunity
Elham Ben Saad, Andres Oroya, Nikhil Ponnoor Anto, Meriem Bachais, Christopher E. Rudd
This study shows that PD-1 internalization enhances the cytolytic potential of checkpoint blockade by removing PD-1 from T-cells, improving anti-tumor immunity.
Cell Reports · Oct 30, 2024Peer-reviewedImmunology