Author

Andres Oroya

Hôpital Maisonneuve-RosemontORCID 0000-0002-9012-3041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Christopher E. RuddiD· 2 shared Nikhil Ponnoor AntoiD· 2 shared Alexandra KazanovaiD· 1 shared Auryane Laure Cabald· 1 shared Bastien Moës· 1 shared Chen LiuiD· 1 shared Elham Ben Saad· 1 shared Janna KruegeriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Christopher E. RuddORCID

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2 papers

Recent·Most cited

GSK-3 regulates CD4-CD8 cooperation needed to generate super-armed CD8+ cytolytic T cells against tumors

Bastien Moës, Janna Krueger, Alexandra Kazanova, Chen Liu, Yunfeng Gao, Nikhil Ponnoor Anto, Linda Castoun-Puckett, Andres Oroya, Lan Huong, Auryane Laure Cabald, Thai Hien Tu, Christopher E. Rudd

This study shows GSK-3 enhances PD-1 blockade by promoting CD4-CD8 T-cell cooperation, leading to more effective anti-tumor CD8+ cytolytic T cells.

bioRxiv · Mar 8, 2025 · PreprintImmunology

PD-1 endocytosis unleashes the cytolytic potential of check-point blockade in tumor immunity

Elham Ben Saad, Andres Oroya, Nikhil Ponnoor Anto, Meriem Bachais, Christopher E. Rudd

This study shows that PD-1 internalization enhances the cytolytic potential of checkpoint blockade by removing PD-1 from T-cells, improving anti-tumor immunity.

Cell Reports · Oct 30, 2024Peer-reviewedImmunology