Christopher E. Rudd

This study shows that vascular activation precedes immune cell infiltration in corneal alkali burns, with sex-dependent differences in vascular permeability and lymphatic remodeling.

This study shows GSK-3 enhances PD-1 blockade by promoting CD4-CD8 T-cell cooperation, leading to more effective anti-tumor CD8+ cytolytic T cells.

The paper identifies a SARS-CoV-2 S2 protein-derived peptide (P3) with super-antigen-like properties that stimulate T-cells and induce proinflammatory cytokines in mice.

This study shows that PD-1 internalization enhances the cytolytic potential of checkpoint blockade by removing PD-1 from T-cells, improving anti-tumor immunity.

This study shows that anti-PTHrP therapy reduces T-cell exhaustion and enhances cytolytic protein expression in melanoma, suggesting it could improve cancer immunotherapy.