AquIRE reveals multiple mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs
Zijian Zhang, Zornitsa Vasileva Kotopanova, Kexin Dang, Xiangxu Kong, Nicole Simms, Tin Wai Yuen, Aynur Soenmez, Lauren Forbes Beadle, Emma N. Hilton, Taqdees Qureshi, Marianna Coppola, Callum David Holmes, Kwan Ting Kan, Mark Ashe, Patrick Gallois, , John R. P. Knight
The paper develops AquIRE to quantify RNA damage and identifies multiple mechanisms of clinically induced RNA modifications, including glycoRNA dynamics across life kingdoms.
bioRxiv · Apr 1, 2025 · PreprintMolecular Biology