Lauren Forbes Beadle

The paper identifies and validates binding epitopes in Twisted gastrulation (Tsg) that mediate interaction with Sog/Chordin, revealing an avidity-driven mechanism for BMP gradient formation.

The paper develops AquIRE to quantify RNA damage and identifies multiple mechanisms of clinically induced RNA modifications, including glycoRNA dynamics across life kingdoms.

The paper shows spatially regulated mRNA decay sharpens the even-skipped expression pattern in Drosophila embryos by improving stripe definition and affecting segmentation.

This paper introduces a MiMIC-based method to rapidly insert MS2/PP7 cassettes into Drosophila genes for live transcription imaging, expanding the tissues and genes that can be studied.

The paper investigates how transcription burst amplitude modulation mediates dosage compensation in Drosophila embryos by analyzing gene expression dynamics.

The paper estimates mRNA half-lives in Drosophila embryos using RNA-seq time series and Gaussian process regression, showing correlations between mRNA stability and P-body association.

This study shows that insulin-like signaling coordinates Drosophila larval hemocyte number with body size, with reduced growth rate and impaired signaling leading to fewer hemocytes.