Pan-cancer proteomic map of 949 human cell lines reveals principles of cancer vulnerabilities
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth Srinivas Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer M.S. Koh, Howard W. Lightfoot, Sadia Mahboob, Iman D. Mali, , Roger R. Reddel
The paper presents a pan-cancer proteomic map of 949 cell lines, revealing protein-specific biomarkers of cancer vulnerabilities and showing proteomic data's superior predictive power for drug response.
Cancer Cell · Jul 14, 2022Peer-reviewedSystems Biology