Dörte Becher

HERC4 limits oxidative stress-induced DNA damage during bacterial and viral-bacterial infection

The paper identifies HERC4 as a regulator of ROS-induced DNA damage during bacterial and viral-bacterial infections, showing its role in DNA repair and potential as a therapeutic target.

Spatial constraints drive amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon

The paper investigates how spatial constraints and enzyme composition regulate amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon.

RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets

RAPDOR uses Jensen-Shannon distance to analyze complex proteomics datasets, identifying RNA-binding proteins in cyanobacteria and showing its utility in stress-induced protein redistribution.

Transformation of the drug ibuprofen by Priestia megaterium: Reversible glycosylation and generation of hydroxylated metabolites

This paper identifies two main biotransformation pathways of ibuprofen by Priestia megaterium, including hydroxylation and reversible glycosylation, and shows their potential role in detoxification.

Spatiotemporal Dynamics of the Dihydrolipoyl Dehydrogenase LpdA Determine the Intrinsic Autofluorescence in Filamentous Actinobacteria

The paper identifies LpdA as the source of intrinsic autofluorescence in filamentous actinobacteria and shows its role in metabolic organization during growth.

Resource partitioning in organosulfonate utilization by free-living heterotrophic bacteria during a North Sea microalgal bloom

This study analyzes metagenomic, metatranscriptomic, and metaproteomic data from a North Sea microalgal bloom to show resource partitioning among bacterial clades utilizing different organosulfur compounds.

Marine Gammaproteobacteria use SusC/D-like proteins in fructan utilization

This study identifies SusC/D-like proteins in marine Gammaproteobacteria for fructan utilization, challenging the notion that these proteins are exclusive to Bacteroidota.

The microbiome of the lichen Lobaria pulmonaria varies according to climate in Europe

This study examines how the bacterial microbiome of the lichen Lobaria pulmonaria varies with climate across Europe, finding that climatic factors explain more variation than local weather or sampling season.

Small proteome of the nitrogen-fixing plant symbiont Sinorhizobium meliloti

The paper expands the known proteome of Sinorhizobium meliloti by identifying 48 novel small proteins using Ribo-seq and proteogenomics.

A small RNA is linking CRISPR-Cas and zinc transport

The paper identifies a small RNA (s479) in H. volcanii that regulates zinc transport and interacts with CRISPR-Cas components, suggesting a link between CRISPR-Cas and sRNA function.

V. longisporum elicits media-dependent secretome responses with a further capacity to distinguish between plant-related environments

This study identifies media-dependent secretome responses in Verticillium longisporum, revealing specific exoproteome patterns in plant-related environments and identifying Nlp2 and Nlp3 as key effectors for plant infection.

Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated by an Oncogenic Transcription Factor in Acute Myeloid Leukemia

This study uses subtractive interaction proteomics to identify signaling pathways activated by the t(6;9)-DEK/CAN oncogene in AML, revealing potential therapeutic targets.