Author

Michael R Schertzberg

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Andrew G. FraseriD· 3 shared June H. TaniD· 3 shared Margot J. LautensiD· 2 shared Gustavo SalinasiD· 1 shared Jennifer N. ShepherdiD· 1 shared Jianbin WangiD· 1 shared Laura Romanelli-CedreziD· 1 shared Maria P. MercadoiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Andrew G. FraserORCID

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3 papers

Recent·Most cited

Natural variation in expression of the mitochondrial flavoprotein WAH-1 alters response to cyanide in C. elegans

Maria P. Mercado, June H. Tan, Michael R Schertzberg, Andrew G. Fraser

The paper identifies natural variation in wah-1 expression affecting RQDM in C. elegans and shows similar complexity in parasitic nematodes.

bioRxiv · Mar 3, 2023 · PreprintMolecular Biology

Identification of enzymes that are required for Rhodoquinone-dependent metabolism as targets for new species-specific inhibitors

Margot J. Lautens, June H. Tan, Xènia Serrat, Samantha Del Borrello, Michael R Schertzberg, Andrew G. Fraser

The paper identifies 4 helminth-specific enzyme targets for RQ-dependent metabolism that could be inhibited to develop new anthelmintics.

bioRxiv · Mar 24, 2021 · PreprintMolecular Biology

Alternative splicing of COQ-2 determines the choice between ubiquinone and rhodoquinone biosynthesis in helminths

June H. Tan, Margot J. Lautens, Laura Romanelli-Cedrez, Jianbin Wang, Michael R Schertzberg, Samantha R. Reinl, Richard E. Davis, Jennifer N. Shepherd, Andrew G. Fraser, Gustavo Salinas

The paper shows helminths switch from ubiquinone to rhodoquinone synthesis via alternative splicing of coq-2 in anaerobic environments.

bioRxiv · Feb 28, 2020 · PreprintMolecular Biology