PCF11 connects alternative polyadenylation to formation and spontaneous regression of neuroblastoma
Anton Ogorodnikov, Michal Levin, Surendra Mohan Tattikota, Sergey V. Tokalov, Mainul Hoque, Denise Scherzinger, Fédérico Marini, Ansgar Poetsch, Harald Binder, Stephan Macher-Göppinger, Hans Christian Probst, Bin Tian, Michael Schaefer, Karl Johannes Lackner, Frank Westermann, Sven Danckwardt
The paper identifies PCF11 as a critical regulator of alternative polyadenylation in neuroblastoma, linking it to cell fate reprogramming and spontaneous tumor regression.
Nature Communications · Dec 10, 2018Peer-reviewedGenomics