Author

Mainul Hoque

Rutgers New Jersey Medical SchoolORCID 0000-0002-0143-9408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ansgar PoetschiD· 1 shared Anton Ogorodnikov· 1 shared Bin TianiD· 1 shared Dahui WangiD· 1 shared Denise Scherzinger· 1 shared Edward A. GonzaleziD· 1 shared Fédérico MariniiD· 1 shared Frank WestermanniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Ansgar PoetschORCID

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2 papers

Recent·Most cited

Pluripotency and Transcriptional Pausing Disrupt Circadian Rhythms to Facilitate the Enrichment of Cancer Stem Cells

Edward A. Gonzalez, Dahui Wang, Maciej Jeziorek, Shahd Mohamed, Lauren S. Sherman, Premananda Indic, Patricia Soteropoulos, Mainul Hoque, Seth Raphael Goldman, Karen Adelman, Lanjing Zhang, Pranela Rameshwar, Jean‐Pierre Etchegaray

This study shows that disrupting circadian rhythms through pluripotency factors and transcriptional pausing promotes cancer stem cell enrichment in TNBC, correlating with poor patient outcomes.

bioRxiv · Sep 11, 2026 · PreprintCancer Biology

PCF11 connects alternative polyadenylation to formation and spontaneous regression of neuroblastoma

Anton Ogorodnikov, Michal Levin, Surendra Mohan Tattikota, Sergey V. Tokalov, Mainul Hoque, Denise Scherzinger, Fédérico Marini, Ansgar Poetsch, Harald Binder, Stephan Macher-Göppinger, Hans Christian Probst, Bin Tian, Michael Schaefer, Karl Johannes Lackner, Frank Westermann, Sven Danckwardt

The paper identifies PCF11 as a critical regulator of alternative polyadenylation in neuroblastoma, linking it to cell fate reprogramming and spontaneous tumor regression.

Nature Communications · Dec 10, 2018Peer-reviewedGenomics