Programmable RNA-guided endonucleases are widespread in eukaryotes and their viruses
Kaiyi Jiang, Justin Lim, Samantha R. Sgrizzi, Michael Trinh, Alişan Kayabölen, Natalya Yutin, Eugene V. Koonin, Omar O. Abudayyeh, Jonathan S. Gootenberg
The paper identifies widespread RNA-guided nucleases in eukaryotes and their viruses, showing they can be used for genome editing in human cells.
bioRxiv · Jun 13, 2023 · PreprintMolecular Biology