The non-canonical SMC protein SmcHD1 antagonises TAD formation on the inactive X chromosome
Michal Ryszard Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Özadam, Michael W. McClellan, Daniela Moralli, Felix Krueger, Catherine Green, Wolf Reik, Skirmantas Kriaučionis, Édith Heard, Job Dekker, Neil Brockdorff
This study shows that SmcHD1 prevents TAD formation on the inactive X chromosome by altering chromatin structure and epigenetic marks.
Nature Communications · Dec 28, 2018Peer-reviewedMolecular Biology