Prebiotically Plausible Peptides can Self-assemble into beta-rich Assemblies
Mikhail Makarov, Robin Kryštůfek, Matúš Friček, Edgar Manriquez‐Sandoval, Soumya Dutta, Ján Michael Kormaník, Tadeáš Kalvoda, Václav Verner, Lucie Bednářová, Tatsiana Charnavets, Michal Lebl, Sean M. Brown, Romana Hadravová, Jan Konvalinka, Abhishek Singharoy, , Klára Hlouchová
This study shows random 25-mer peptides with a prebiotically plausible amino acid alphabet can self-assemble into thermostable beta-rich nanostructures.
bioRxiv · Nov 9, 2025 · PreprintBiochemistry