Edgar Manriquez‐Sandoval

Prebiotically Plausible Peptides can Self-assemble into beta-rich Assemblies

This study shows random 25-mer peptides with a prebiotically plausible amino acid alphabet can self-assemble into thermostable beta-rich nanostructures.

Protein Surface Chemistry Encodes an Adaptive Tolerance to Desiccation

The paper identifies protein surface chemistry as a determinant of desiccation tolerance and shows that modifying surface amino acids can confer tolerance to otherwise sensitive proteins.

FLiPPR: A Processor for Limited Proteolysis (LiP) Mass Spectrometry Datasets Built on FragPipe

FLiPPR improves LiP-MS data analysis by formalizing data imputation, merging data, and correcting multiple hypotheses, enhancing statistical trends and metadata collection.

Accurate Protein Domain Structure Annotation with DomainMapper

DomainMapper accurately annotates protein domain structures, including non-contiguous and insertional domains, validated against AlphaFold data.