Author

Mihika Jalan

Sangamo BioSciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Amy M. PooleriD· 2 shared Bryan ZeitleriD· 2 shared Kathleen E. MeyeriD· 2 shared Sarah J. HinkleyiD· 2 shared Toufan Parman· 2 shared Yanmei LuiD· 2 shared Alaric Falcon· 1 shared Alex Michael WardiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Amy M. PoolerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Zinc Finger Repressors mediate widespread PRNP lowering in the nonhuman primate brain and profoundly extend survival in prion disease mice

Shih-Wei Chou, Meredith A Mortberg, Kimberly Marlen, David S. Ojala, Toufan Parman, Michael Howard, Kendrick DeSouza-Lenz, Yuan Lian, Mohadeseh Mehrabian, Matthew R. Tiffany, Annemarie Ledeboer, Patrick Dunn, Jing Hu, Kenia Guzman, Nikita Kamath, , Bryan Zeitler

This study demonstrates that Zinc Finger Repressors (ZFRs) reduce prion protein (PrP) expression in nonhuman primates and extend survival in prion disease mice.

bioRxiv · Mar 5, 2025 · PreprintNeuroscience

Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain

Mohammad Samie, Toufan Parman, Mihika Jalan, Jisoo Lee, Patrick J. Dunn, Jason A. Eshleman, Dianna Baldwin Vidales, Josh Holter, Brian Jones, Yonghua Pan, Marina Falaleeva, Sarah J. Hinkley, Alicia Goodwin, Tammy Chen, Sumita Bhardwaj, , Amy M. Pooler

This study demonstrates the use of engineered zinc finger repressors delivered via AAV to reduce SCN9A expression in preclinical models, showing efficacy in reducing neuropathic pain.

bioRxiv · Sep 6, 2024 · PreprintNeuroscience