Cell BiologybioRxivPreprint
Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo
Jessica Perrin, Thilo Werner, Nils Kurzawa…·Giovanna Bergamini
This study introduces tissue-TPP and blood-CETSA to measure proteome thermal stability, revealing organ physiology and drug-target engagement in vivo.
DOI 10.1101/500306