D-alanine aminotransferase (Dat) promotes Staphylococcus aureus colonization fitness on human nasal respiratory epithelium
Andrea I. Boyd, Katia A. Quintanilla, Isabel F. Escapa, Millie A. Lewis, Leah A. Kafer, Xi‐Lei Zeng, Sarah Elizabeth Blutt, Carolyn B. Ibberson, Katherine P. Lemon
This study identifies D-alanine aminotransferase (Dat) as critical for Staphylococcus aureus colonization of human nasal epithelium, showing its role in D-alanine production and fitness in this environment.
bioRxiv · Jun 4, 2026 · PreprintMicrobiology