BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences
Sanad M. El-Khatib, Arya R. Vagadia, Anh C. D. Le, Ding Quan Ng, Janet E. Baulch, Mingyu Du, Zhiqun Tan, Xiangmin Xu, Alexandre Chan, Munjal M. Acharya
This study shows that riluzole improves cognitive function and reduces neurodegeneration in mice after cranial radiation therapy by increasing BDNF levels and reducing neuroinflammation.
bioRxiv · Sep 23, 2024 · PreprintNeuroscience